run.sh - Скрипт для запуска создания файлов и перезапуска Nginx, Apache2:

#!/bin/sh
cd  /home/admin/www/_default/
php /home/admin/www/_default/conf.php
/etc/init.d/nginx restart
/etc/init.d/apache2 restart
echo "The end"

domains.txt - список доменов:

домен1.ru
домен2.ru
домен3.ru

conf.php - Генератор конфигов на PHP:

<?php
$domains = explode("\n", file_get_contents("domains.txt"));


$tmpl_apache='
<VirtualHost *:81>
	ServerAdmin webmaster@localhost
	
	ServerName _host_
	ServerAlias www._host_

	<IfModule mpm_itk_module>
	AssignUserId admin www-data
	</IfModule>

	DocumentRoot /home/admin/www/_host_/

	<Directory /home/admin/www/_host_>
		Options Indexes FollowSymLinks All MultiViews 
		AllowOverride All
	</Directory>

	ErrorLog  /home/admin/logs/_host_-error_log

</VirtualHost>
';


$tmpl_nginx = '

	server {
		listen 80;
		server_name  ##domain## ##domain_aliases##;

		location /block.png
		{
		    gzip off;
		    default_type image/png;
		    root /home/##user##/www/##domain##;
		}


				
		location ~* ^.+\.(swf|xml|jpg|jpeg|gif|png|ico|css|zip|tgz|gz|rar|bz2|doc|xls|exe|pdf|ppt|txt|tar|wav|bmp|rtf|js|ods|arj|htc|avi|mpg|mp3|mid)$ {
	           valid_referers none blocked server_names ~\.google\. images.yandex.ru;
		    if ($invalid_referer) 
		    {
			return 404;
			#rewrite /(.*)\.(gif|jpg|jpeg|png)$ / break;
			#rewrite ^(.*)$ /block.png break;
		    }
		    
		    root    /home/##user##/www/##domain##;
		    
		} 
		location ~ \.flv$ { 
			root        /home/##user##/www/##domain##;
			flv;
		}


		location / {
			proxy_pass          http://127.0.0.1:81;
			proxy_set_header    X-Real-IP  $remote_addr;
			proxy_set_header    X-Forwarded-For  $proxy_add_x_forwarded_for;
			proxy_set_header    X-Accel-Internal /internal_xxx;
			proxy_set_header    Host $http_host;
			proxy_redirect  	http://##domain##:81/  /;
		}		
		
		location ~ /\.htp { deny  all; }
		location ~ /\.hta { deny  all; }
		location ~ /\.svn { deny  all; }
		location /stub_status { stub_status on; access_log off;}
	}

';

foreach($domains as $d)
{
	if(strlen($d)>3)
	{
	$d = strtolower(trim($d));
	$path = "/home/admin/www/".$d."/";
	if(!file_exists($path))mkdir($path, 0755);


	$domain_aliases = "www.".$d;
	$user="admin";
	//##domain## ##domain_aliases##
	$s = str_replace("_host_",$d,$tmpl_apache);
	$n = str_replace("##user##",$user,$tmpl_nginx);
	$n = str_replace("##domain##",$d,$n);	
	$n = str_replace("##domain_aliases##",$domain_aliases,$n);

	//echo $s;
	$app_conf.=$s;
	$nginx_conf.=$n;
	}
}

echo file_put_contents("../apache_sites.conf", $app_conf);
echo file_put_contents("../nginx_sites.conf", $nginx_conf);
echo "ok";